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  • Title: [Properties of endoribonuclease activity of proteasomes from K562 cells. III. The specific endonuclease activity of ribonucleoprotein particles (alpha-RNP) tightly bound to chromatin and containing 20S proteosomes].
    Author: Mittenberg AG, Kulichkova VA, Gauze LN, Konstantinova IM.
    Journal: Tsitologiia; 2002; 44(4):364-8. PubMed ID: 12149780.
    Abstract:
    The present work demonstrates the ability of 20S proteasome-containing, tightly bound to chromatin RNP-particles (alpha-RNP) to endonucleolyse specific messenger RNAs (in particular, human mRNA for p53 gene and mRNA for luciferase from Renilla sp.). The dependence of individual mRNA endonucleolysis by alpha-RNP particles on both the substrate and enzyme was found.
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