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  • Title: [The lung and the metabolism of vasoactive substances].
    Author: Junod AF.
    Journal: Schweiz Med Wochenschr; 1975 Dec 06; 105(49):1656-8. PubMed ID: 1215952.
    Abstract:
    The lung is the site of a number of reactions affecting vasoactive substances: hydrolysis of angiotensin I, bradykinin and ATP, occurring at the surface of endothelial cell; uptake and intracellular metabolism of 5-hydroxytryptamine and norepinephrine; and intracellular oxidation of prostaglandins. Mediators, including prostaglandins, histamine and SRS-A (slow reacting substance of anaphylaxis), can also be released from the lung. The possible implications of these recent findings are analysed.
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