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  • Title: Osmotic myelinolysis in a normonatremic patient.
    Author: Kilinç M, Benli US, Can U.
    Journal: Acta Neurol Belg; 2002 Jun; 102(2):87-9. PubMed ID: 12161906.
    Abstract:
    Osmotic demyelination syndrome is usually associated with hyponatremia or rapid correction of this condition. The prognosis is usually fatal. We treated a 34-year-old chronic renal failure patient who did not have hyponatremia but developed severe pontine myelinolysis demonstrated with MRI. Serial MRI revealed gradual reduction of the lesions over 2 months. This case demonstrates that osmotic demyelination syndrome is not always associated with hyponatremia, and that, although the prognosis is usually poor, some patients recover.
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