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  • Title: [Neuroradiological differential diagnosis in medulloblastomas and ependymomas: results of the HIT'91-study].
    Author: Warmuth-Metz M, Kühl J.
    Journal: Klin Padiatr; 2002; 214(4):162-6. PubMed ID: 12165896.
    Abstract:
    BACKGROUND: Imaging criteria of medulloblastomas and ependymomas were defined retrospectively to allow a preoperative differential diagnosis of these malignant tumors of the posterior fossa. PATIENTS AND METHODS: CT and/or MR-studies of 103 patients with medulloblastomas and 19 ependymomas treated in the HIT'91-trial were centrally reviewed. Evaluation concerned the origin, CT-density or MR-signal intensity, enhancement, internal structural homogeneity and results of staging of the tumors. RESULTS: Medulloblastomas and Ependymomas showed different results concerning all imaging criteria. CONCLUSION: On the basis of differences in localisation, enhancement and tumor growth in most cases a preoperative differential diagnosis between medulloblastomas and ependymomas is possible. Increased density on CT allows the differentiation of the malignant tumors from pilocytic astrocytomas of the fourth ventricle.
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