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  • Title: Mitomycin-C induced hemolytic uremic syndrome: a case report.
    Author: Gundappa RK, Sud K, Kohli HS, Gupta KL, Joshi K, Sakhuja V.
    Journal: Ren Fail; 2002 May; 24(3):373-7. PubMed ID: 12166705.
    Abstract:
    Mitomycin-C is used widely in the treatment of malignancies and is associated with serious dose related adverse effects including the occurrence of hemolytic uremic syndrome. We report a patient with a colonic adenocarcinoma who developed hemolytic uremic syndrome after receiving 85 mg/m2 of the drug. The patient was left untreated and died 5 months after this diagnosis was made, of a second malignancy. Differential diagnosis and treatment of this condition are discussed.
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