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  • Title: The effect of ATP on lactic dehydrogenase (LDH) activity and influenza B virus multiplication.
    Author: Prahoveanu E, Petrescu A, Moisa I.
    Journal: Virologie; 1975; 26(1):51-5. PubMed ID: 1216689.
    Abstract:
    The authors investigated the effect of ATP, an energy supplying substance, on the activity of LDH, an enzyme of the glycolytic pathway and on the multiplication of influenza virus strain B/Singapore in embryonate hen eggs. In the presence of ATP the increase in LDH activity could be detected from the first 1-3 hours and became obvious after 24 hours; likewise, virus multiplication was more intensive so that the hemagglutinating (HA) activity appeared 12 hours earlier than in controls and the increased HA values persisted for a longer time. The isoenzymatic pattern showed an intensification of LDH4 and LDH5 fractions in virus-inoculated eggs.
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