These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Cochlear and vestibular risk at high altitude].
    Author: Mees K, Suckfüll M.
    Journal: Laryngorhinootologie; 2002 Jul; 81(7):465-8. PubMed ID: 12173056.
    Abstract:
    Exposure to lowered oxygen pressure at high altitude results in various physiological reactions. The most important response besides hyperventilation is the elevation of the oxygen transport capacity, which simply is achieved by plasma diuresis. Hemoconcentration however not only increases oxygen uptake but also raises blood viscosity, serum osmolality and impairs blood flow. Various observations have suggested that hearing and postural properties deteriorate under these conditions at high altitude. Studies in hypobaric chambers and our own data indicate that the elevated hematocrit levels and hypoxemia may impair the central nervous system functions, resulting in altered speech discrimination, directional hearing, and postural control. However, there is no evidence that cochlear and vestibular sensory cells are affected, whether by acute hypoxia, nor by elevated hematocrit levels up to 58 %. Even an greater increase in serum osmolality or an impaired osmoregulation may not interfere with the outer hair cell function resulting in threshold shift and hearing loss.
    [Abstract] [Full Text] [Related] [New Search]