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  • Title: Necrotizing granulomatous vasculitis associated with cocaine use.
    Author: Gertner E, Hamlar D.
    Journal: J Rheumatol; 2002 Aug; 29(8):1795-7. PubMed ID: 12180747.
    Abstract:
    Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction. This report is the first to document a necrotizing granulomatous vasculitis associated with nasal destruction and an oronasal fistula in a chronic cocaine user. Cocaine is an environmental insult that may play a role in triggering cerebral and non-cerebral vasculitis including a necrotizing granulomatous vasculitis of the respiratory tract.
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