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Title: Congenital Spitz nevus clinically mimicking melanoma. Author: Zaenglein AL, Heintz P, Kamino H, Zisblatt M, Orlow SJ. Journal: J Am Acad Dermatol; 2002 Sep; 47(3):441-4. PubMed ID: 12196758. Abstract: The differentiation between atypical variants of Spitz nevus and melanoma is often difficult given the many clinical and histopathologic similarities between the two. We report a case of an infant with a congenital scalp lesion exhibiting clinical features of melanoma, including variegation and regression of pigmentation and a rapidly changing appearance. Histologic examination of the excised lesion revealed a benign congenital Spitz nevus. This case emphasizes the need for clinical and histologic correlation in determining the benign or malignant nature of atypical pigmented lesions in infants.[Abstract] [Full Text] [Related] [New Search]