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  • Title: No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer Disease.
    Author: Liou YJ, Hong CJ, Liu HC, Liu CY, Liu TY, Chen IC, Tsai SJ.
    Journal: Am J Med Genet; 2002 Aug 08; 114(6):687-8. PubMed ID: 12210288.
    Abstract:
    Nitric oxide synthase (NOS) has been implicated in the pathogenesis of Alzheimer disease (AD). To examine the role of the neuronal NOS (nNOS) gene in AD, patients (n = 139) and control subjects (n = 101) were genotyped for the nNOS dinucleotide polymorphism. No association was demonstrated for AD and this particular nNOS polymorphism.
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