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  • Title: [A study on nasal absorption of psoralen and isopsoralen in Psoralea corylifolia L].
    Author: Li A, Wang H.
    Journal: Zhongguo Zhong Yao Za Zhi; 1999 Nov; 24(11):689-91, 704. PubMed ID: 12212091.
    Abstract:
    OBJECTIVE: To investigate the nasal absorption regularities of psoralen and isopsoralen of different concentrations. METHOD: Building an experimental model of rat in situ nasal recirculation and determining the contents of psoralen and isopsoralen by HPLC. RESULT: The nasal absorption of psoralen and isopsoralen fitted in with zero order kinetics, getting saturated with the increase of concentration. CONCLUSION: A suitable concentration is necessary for the preparation of nasal remedies psoralen and isopsoralen.
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