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  • Title: [Detection of D -dimer in pleural effusion].
    Author: Lü YD, Chen P, Xu M.
    Journal: Hunan Yi Ke Da Xue Xue Bao; 2000 Feb 28; 25(1):71-2. PubMed ID: 12212257.
    Abstract:
    The content of D -dimer in pleural fluid of different causes was examined by the ELISA method in 45 patients. The results were that the contents of D -dimer in both tuberculous and empyema pleural effusions were significantly higher than in malignant pleural effusion (P < 0.01; P < 0.05). D -dimer was positively correlated with lactic dehydrogenase (LDH) in pleural fluid (r = 0.4168, P < 0.01). The results suggest that fibrinolytic activities in tuberculous and empyema pleural effusion are much higher than in malignant pleural effusion. The detection of D -dimer in pleural fluid may reflect the extent of pleural inflammation and be helpful in the differential diagnosis of pleural effusion.
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