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  • Title: [SAPHO syndrome: case report of an 18-year-old man and review of the literature].
    Author: Wolf G, Aigner RM, Schwarz T, Lorbach MP.
    Journal: Wien Klin Wochenschr; 2002 May 15; 114(8-9):341-4. PubMed ID: 12212370.
    Abstract:
    We report about an 18-year-old man, suffering from acne on his face and trunk and complaining about indefinite bone pains--without any trauma. SAPHO-syndrome was diagnosed which consists of synovitis, acne, pustulosis, hyperostosis and osteitis. Five types of this syndrome can be differentiated: spondarthritis hyperostotica pustulo-psoriatica, chronic recurrent multifocal osteomyelitis, inflammatory chest wall syndrome, isolated sternocostoclavicular hyperostosis, and the combined form of acne-associated spondarthritis and chronic recurrent osteomyelitis. Although the sapho-syndrome is very rare, it should be considered a possible diagnosis in the case of indefinite bone pains in combination with acne, pustulosis and hyperostosis.
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