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  • Title: [A study on anti-caries activity of genetic recombinant vaccine of Streptococcus lactis. II. Immunization in vein with recombinant S. lactis in pregnant rabbits].
    Author: Liu J, Fan M, Bian Z, Ling J.
    Journal: Hua Xi Kou Qiang Yi Xue Za Zhi; 1998 May; 16(2):108-10, 140. PubMed ID: 12214406.
    Abstract:
    The effects of immunization in vein with recombinant S. lactis HL107 carring the S. mutans surface protein PAc gene in pregnant rabbits were studied. The results indicated that specific anti-PAc IgG in serum and milk were obviously induced 1 week after immunization and retained at high level for several weeks. It suggests that the recombinant S. lactis HL107 possessing immunogenicity of S. mutans surface protein PAc is able to stimulate specific systemic immune response against PAc.
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