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  • Title: [Ultrastructural and functional expression of the hepatocyte genome in conditions of prolonged suppression by cycloheximide of protein synthesis. IV].
    Author: Galkin AP, Shen RA, Todorov IN.
    Journal: Tsitol Genet; 1975; 9(6):533-7. PubMed ID: 1221578.
    Abstract:
    RNA synthesis was intensified in isolated nuclei of the rat liver an hour after the animal treatment with cycloheximide (CHI). Incubation of the nuclei with a cytoplasmic fraction 160000 g obtained from normal rats decreases RNA synthesis, and that obtained from CHI-treated animals-increases it. Mechanisms of this effects are discussed.
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