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  • Title: Saccopetrins A and B, two novel gamma-lactones from Saccopetalum prolificum.
    Author: Wang ML, Du J, Zhang PC, Chen RY, Xie FZ, Zhao B, Yu DQ.
    Journal: Planta Med; 2002 Aug; 68(8):719-22. PubMed ID: 12221595.
    Abstract:
    Two new gamma-lactones, saccopetrin A (1) and saccopetrin B (2), together with 10 known compounds have been isolated from the roots of Saccopetalum prolificum. Their structures were established by spectroscopic and chemical methods. The absolute configuration of 1 was determined by chemical transformation and the Mosher method. Cytotoxic activities were evaluated against several different cell lines. Compound 2 exhibited stronger cytotoxic activities than 1 against KB and HCT-8 cell lines at a concentration of 10(-5) mol/L.
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