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  • Title: Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
    Author: Ho SE, Subramaniam G, Palasubramaniam S, Navaratnam P.
    Journal: Antimicrob Agents Chemother; 2002 Oct; 46(10):3286-7. PubMed ID: 12234862.
    Abstract:
    We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant.
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