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Title: An ion conductor that recognizes osmotically-stressed phospholipid bilayers. Author: Bandyopadhyay P, Bandyopadhyay P, Regen SL. Journal: J Am Chem Soc; 2002 Sep 25; 124(38):11254-5. PubMed ID: 12236724. Abstract: A synthetic ion conductor (1), derived from cholic acid and spermine, has been found capable of recognizing osmotic stress in liposomes made from 1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine [(C16:1)PC]. Thus, when large unilamellar vesicles of (C16:1)PC are placed under hypotonic conditions, the Na+/Li+ transport activity of 1 increases by as much as 1 order of magnitude, relative to isotonic conditions[Abstract] [Full Text] [Related] [New Search]