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  • Title: A historical appraisal of the use of cryopreserved and glycerol-preserved allograft skin in the treatment of partial thickness burns.
    Author: Vloemans AF, Middelkoop E, Kreis RW.
    Journal: Burns; 2002 Oct; 28 Suppl 1():S16-20. PubMed ID: 12237059.
    Abstract:
    Two studies into the use of allograft skin in the treatment of partial thickness burn injuries in this burn centre have provided the opportunity to discuss changes and similarities over a 20 year period. The first study described results obtained with cryopreserved allografts in partial thickness burns in the period 1979-1981. The second study concerned patients with partial thickness injuries treated with glycerol-preserved allografts in the period 1998-2000. A reduction was noted concerning the need for secondary autografting in the group treated with glycerolized allografts. The probability that this difference has occurred by chance is small (P=0.089). Various other factors that might account for the differences in outcome, include general improvements in health and social welfare, differences in treatment protocols, and differences in allograft properties. A prospective comparative trial is indicated to study direct differences between the two types of allograft.
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