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  • Title: A sensitive GLC method for the determination of imipramine and desmethylimipramine using a nitrogen detector.
    Author: Cooper TB, Allen D, Simpson GM.
    Journal: Psychopharmacol Commun; 1975; 1(4):445-54. PubMed ID: 1224013.
    Abstract:
    A sensitive method for determination of imipramine and desmethylimipramine using a GLC system fitted with a new nitrogen detector is described. The lower limit of sensitivity is less than 1 ng/ml with a lower limit enabling quantitation with acceptable precision of 3-5 ng/ml. Data from 20 control subjects given a single oral dose of imipramine are shown.
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