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  • Title: [Circulation in bone in Paget's disease. General review and personal results].
    Author: Arlet J, Mazières B.
    Journal: Rev Rhum Mal Osteoartic; 1975 Nov; 42(11):643-6. PubMed ID: 1224150.
    Abstract:
    On the basis of a review of work concerned with the circulation in bones affected by Paget's disease and from their own results, the authors show that the vascularization of affected by Paget's disease is completely different from that of normal bone. The periostal vessels are abnormally developed and result in a high flow in the affected limb. The cortical vessels are numerous and of all types, forming a system of canalization of considerable volume. On the other hand the medullary circulation is encumbered by stasis, oedema, and fibrosis. The earliness of the vascular lesions makes it possible to envisage a vascular theory in connection with Paget's disease.
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