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  • Title: [Disaccharidases of the small intestine mucosa in infants and children. "Normal values", log normal distribution and age dependence].
    Author: Niessen KH, Schmidt K, Brügmann G.
    Journal: Z Gastroenterol; 1975 Oct; 13(6):565-72. PubMed ID: 1224750.
    Abstract:
    In 63 infants and children with a histological normal mucosa of the duodenum, without an isolated defect of enzyme and with a normal increase of xylose and glucose in serum after a combined xylose-lactose loading test the activities of disaccharidases were log normal distributed. The asymmetric distributions were transformed into symmetric ones and the geometric mean (x) as well as the range (+/- 2 s) of maltase, saccharase, isomaltase, lactase and trehalase were calculated. Only the activity of lactase shows a significant dependency on age. In the first year of age the lower limit (x -- 2 s) of this enzyme is much higher than later.
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