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  • Title: [Hormonal phenomena of the perimenopause].
    Author: Netter A.
    Journal: Contracept Fertil Sex (Paris); 1979 Nov; 7(11):815-6. PubMed ID: 12261682.
    Abstract:
    Perimenopause is characterized by irregular menstrual cycles, and by the appearance of the so called hot flashes. A study of 125 perimenopausal women, and a measurement of the secretion of ovarian and gonadotropin hormones has revealed several possibilities; 1) FSH (follicle stimulating hormone) and LH (luteinizing hormone) reach high levels, while level of estradiol is low; 2) high levels of FSH and LH with high levels of progesterone; and, 3) normal levels of FSH and LH and very high levels of estradiol. Pulsatory secretion is irregular, and endometrial state reflects the inertia of the system.
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