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  • Title: Instant effect of therapeutic abortion on serum steroid hormones during first trimester.
    Author: Kisnisci HA, Ayhan A, Yucebilgin S, Beksac MS, Sefercioglu A, Tasarkan K.
    Journal: Acta Reprod Turc; 1980 Jan; 1(3):80-4. PubMed ID: 12262089.
    Abstract:
    Study focus was on the instant effect of therapeutic abortion under general anesthesia on serum levels of estradiol, progesterone and testosterone during the 1st trimester. Patients were 20 healthy women. Gestational age was determined clinically by the obstetrician on the basis of the menstrual history and estimation of the size of the uterus. The procedure was cervical dilatation by Hegar's dilators and curettage under general anesthesia. Venous blood samples were taken from each patient before dilatation and curettage and 3 hours after the termination of the procedure. In all samples serum estradiol, testosterone and progesterone levels were determined by radioimmunoassay. There was no significant correlation between the preoperative and postoperative serum estradiol, progesterone and testosterone levels. On the basis of the study findings it was concluded that there was no sudden effect of general anesthesia and therapeutic abortion on the serum estradiol, progesterone and testosterone levels. A 3-hour interval may be insufficient for the change of steriod hormones in serum samples.
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