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  • Title: [Effect of naphthenic acids on the permeability of ascitic tumor cells to potassium ions].
    Author: Slivinskiĭ GG, Artamonov AF, Goriaev MI.
    Journal: Tsitologiia; 1975 Nov; 17(11):1283-8. PubMed ID: 1226561.
    Abstract:
    Ascite cells were treated with naphthenic acid preparation, containing a mixture of naphthenic acids with average molecular weight equal to 240, and with a fraction of this preparation differing in the boiling temperature. A 5-10(-7)M and higher concentrations of the preparation and its fraction brought about an increased permeability in ascite cells for K-ions. The effectiveness of naphthenic acids is associated with their hydrophobic properties, which was characterized in the present communication by the value of hydrophilic-lipophilic balance calculated according to the Davies formula.
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