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  • Title: [Production of a noninfectious ornithosis hemagglutinin preparation].
    Author: Vishniakova LA.
    Journal: Vopr Virusol; 1975; (6):741-4. PubMed ID: 1226714.
    Abstract:
    One of the main obstacles to introduction of the HI test in to extensive use is the high infectivity of the causative agent suspensions used as the source of hemagglutinin (HA). The sterilizing effect of UV-rays, high temperature (56 -60 degrees C) and beta-propiolactone was studied in attempts at preparation of noninfectious ornithosis HA. Only BPL was found to be effective. By this method of treatment of the allantoic fluid a noninfectious preparation of ornithosis HA was obtained which was highly active and stable upon storage. It may be used for diagnostic studies in clinical laboratories.
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