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  • Title: [The value of the Coxsackie B virus complement fixation test (author's transl)].
    Author: Hofmann H.
    Journal: Wien Klin Wochenschr; 1975 Dec 26; 87(24):819-22. PubMed ID: 1226771.
    Abstract:
    Enteroviruses were isolated from 27 patients during 1973 and 1974, 21 of these were Coxsackie B, 4 were ECHO and 2 were polio viruses, 5 further viruses could not be identified. Sera from 14 of the Coxsackie patients were investigated twice by means of the Complement Fixation Test (CFT). 11 of them showed a significant rise in antibody titre against one of the 6 different Coxsackie B viruses. No strong correlation was established between the result of the CFT and the isolated type of virus. Nevertheless, the CFT can be helpful in the diagnosis of a Coxsackie B infection. About 200 such cases with varied clinical features were diagnosed in the Department of Virology, Vienna University over the past 3 years by means of the CFT.
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