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  • Title: [Endometrial cytology of IUD smears: endometrial reaction study].
    Author: Salome N, Rezende CD, Peixoto RM, Rocha AH.
    Journal: J Bras Ginecol; 1986; 96(6):263-6. PubMed ID: 12268684.
    Abstract:
    The objective of this research was to ascertain possible abnormal endometrial reactions to the IUD. The Family Planning Clinic of the Gynecology and Obstetrics Department of the Federal University of Minas Gerais, Brazil, used 110 cases from patients with IUDs who used the clinics from July 1981 to December 1982. Pap smears from 102 of these cases were made from material contained on the IUD. Several parameters were used, represented by endometrial cells and associated elements, including the IUD model, the user's age, and the day of the menstrual cycle on which the IUD was removed. The breakdown of endometrial cells was greater in Lippes Loop users than in TCu 200 and Copper 7 users. There was no significant difference in the amount of endometrial cells in the various stages of the menstrual cycle. The large number of cells in 90% of the smears leads to the suggestion that these smears be used for determining exclusion or diagnosis of cancer in the perimenopausal age group when the IUD is removed. A special histiocyte reaction was evident only in Lippes Loop users. A greater frequency of plasmocytes and leukocytes in the pre- and postmenstrual stages should be considered as physiological. A greater frequency of plasmocytes was found in Lippes Loop users, and a smaller frequency of lymphocytes observed from the 8th to 14th days of the menstrual cycle should be considered physiological. The lymphocytes were more frequent in users of the TCu 200 and Copper 7, but not significant enough to suggest the use of medicated IUDs.
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