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  • Title: Lack of data on morning after pill confounds clinicians.
    Journal: Contracept Technol Update; 1987 Nov; 8(11):137-40. PubMed ID: 12269058.
    Abstract:
    Over 40% of clinicians responding to Contraceptive Technology Update's Oral Contraceptive Survey of 1986 reported providing oral contraceptives (OCs) for postcoital contraception. The regimen of choice is 2 Ovral OCs administered within 72 hours of unprotected intercourse followed by 2 more pills 12 hours later. Although interest in and acceptance of prescription of combined OCs for postcoital contraception have grown, clinician are bothered by the paucity of clinical research on this topic. There is particular concern about the relative effectiveness of various administration patterns for Ovral and in the use of other combined OCs, such as ON 7/7/7 and Lc/Ovral. There is some indication, for example, that a longer treatment period with Ovral may be more effective when unprotected intercourse occurs during the latter half of the fertile period. Others have suggested that treatment can be delayed as long as 96 hours after unprotected coitus and still be effective. However, the research that would confirm or refute these points has not been conducted. Another question that requires clinical investigation is whether vaginal administration of postcoital OCs would reduce the incidence of side effects such as nausea and vomiting. Limited research on the postcoital use of combined OCs, and the lack of a written protocol, appear to be hindering the more widespread prescription of this method of menstrual induction. In addition, many clinicians are further deterred by the fact that the US Food and Drug Administration has not approved Ovral as a postcoital contraceptive and the resultant fear of litigation.
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