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  • Title: [Mechanisms of catecholamine synthesis disorders in the adrenals of rats subjected to physical fatigue].
    Author: Matlina EA, Vaĭsman SM, Bykhovskaia KM, Vasil'ev VN.
    Journal: Biull Eksp Biol Med; 1975 May; 79(5):34-6. PubMed ID: 1227589.
    Abstract:
    There was a depression of transformation of noradrenaline, DOPA and thyrosine added in vitro, into catecholamines in the adrenal glands of rats after swimming for a period of 8 hours. This permitted to suppose a depression of the activity of phenylethanolamine-N-methyl-transpherase, DOPA-decarboxylase, and, possibly, of tyrosine hydroxylase under these conditions. After the end of swimming, in the presence of 1-tyrosine, there is at first an activation of noradrenaline synthesis, and then there occurs a gradual normalization (on the 7th day) of adrenaline formation. In rats trained for a period of 2 months the extent of reduction of the catecholamine synthesis in the adrenal glands in response to the 8-hour swimming was much less in comparison with the untrained aniamals.
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