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  • Title: [Proliferation of piriform neurons in the rat cerebellar cortex in the pre- and postnatal periods of development].
    Author: Volkova RI.
    Journal: Biull Eksp Biol Med; 1975 Oct; 80(10):117-9. PubMed ID: 1227607.
    Abstract:
    The method of histoautoradiography with the use of H3-thymidine was applied to the study; there were established the periods of appearance in the cerebellar anlage of albino rats of neuroblasts differentiated into the piriform neurones of the cerebellar cortex; dynamics of the proliferative activity of these cellular elements in the course of the pre- and postnatal periods of development of the experimental animals was investigated. On the basis of the material obtained a conclusion was drawn that the last cell divisions (the result of cell differentiation were Purkinje's cells of the cerebellar cortex) stopped by the 13th--15th day of the embryonic development. No incorporation of the labeled precursor into the DNA of the nuclei of the differentiating piriform neurons occurred later.
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