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  • Title: [Antiheparin properties of synthetic polycations].
    Author: Dubovik VV, Etlis VS, Baluda VP, Sushkevich GN, Shevchuk AS.
    Journal: Farmakol Toksikol; 1975; 38(2):193-8. PubMed ID: 1227887.
    Abstract:
    The toxicity of differently structured polymeric compounds for mice (intravenously) and their antiheparin properties in in vitro and in vivo tests were studied. The antiheparin activity display polymers containing amino groups or onium atoms of nitrogen, sulphur and phosphorus in various structures. The antagonism to heparin is due to the polymers being endowed with polycationic properties.
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