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Title: Clinical experience with Progestasert beyond one year of use. Author: Wan LS. Journal: Contracept Deliv Syst; 1981 Jul; 2(3):243-8. PubMed ID: 12278911. Abstract: A total of 254 women were enrolled in the study of the intrauterine progesterone system, Progestasert, and some of the subjects have been followed into the 8th year of use of the device. Clinical experience on 192 women in their 1st year of use of the device was reported in 1977. This follow-up study reports on 110 patients who had at least 2 insertions of the Progestasert for continuous use of 13 months, to a maximum of 8 insertions for continuous use of up to 86 months, for a total of 3808 months. 60% of subjects were nulliparous women who tolerated the device as well as the multiparous. The expulsion rate was low (3.5/100 women-years) noting that 82% of expulsions occurred within 2 months postinsertion or exchange of the device. A total of 7 pregnancies were observed; the pregnancy rate was 2.2/100 women-years. 2 of these 7 pregnancies were ectopic. No uterine or cervical perforations and no serious infections were observed.[Abstract] [Full Text] [Related] [New Search]