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Title: AIDS wanes in West, grows in Africa and Asia. Journal: AIDS Wkly Plus; ; ():14. PubMed ID: 12290706. Abstract: Worldwide, at least 22 million people have been infected with HIV. The overwhelming majority of these cases, however, are in sub-Saharan Africa, Thailand, and India; approximately 15-20 million people are infected with the total number rapidly increasing. Approximately two million people are infected in the West, and the rate and extent of HIV infection are either plateauing or decreasing. In the West, HIV is contracted primarily through homosexual contact and IV drug use. HIV1-B is the prevalent strain of HIV in such settings. HIV in South Asia and sub-Saharan Africa, however, is mainly transmitted through heterosexual contact and consists of HIV-1 strains A, C, and E. There are therefore two distinct HIV epidemics taking place. Professor Max Essex of the Harvard AIDS Institute noted in his address at a conference on infectious diseases in New Delhi, India, that most planned vaccines and therapy for AIDS were developed in the West and thus targeted to combat HIV1-B. It seems likely, however, that other HIV subtypes will also take hold in the West and that an heterosexual epidemic of considerable magnitude should be anticipated. The high rate of HIV genetic mutation is of concern for both AIDS prevention and treatment. Essex further pointed out that the growing cost of treating AIDS patients with increasingly long lives has prompted a shift in the core of AIDS research from therapy to prevention. That levels of awareness about HIV/AIDS and the extent of sex education among youth are higher in more developed countries compared to in developing countries may play a role in the relatively lower incidence of new HIV cases in the West.[Abstract] [Full Text] [Related] [New Search]