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  • Title: Effect of an oral contraceptive on alpha-tocopherol levels in rat tissues.
    Author: Aftergood L, Fields JE, Alfin-slater RB.
    Journal: Nutr Rep Int; 1976 Feb; 13(2):217-24. PubMed ID: 12307790.
    Abstract:
    The distribution of alpha-tocopherol was studied in female rats receiving .052 mg/day Enovid E for 4 days, and maintained on Vitamin E deficient, adequate, or enriched (10%) diets. The administration of Enovid produced slight increases of alpha-tocopherol in the liver and ovaries of Vitamin-E-deficient animals, and decreases of alpha-tocopherol in the plasma, erythrocytes, adrenals, and kidneys of Vitamin-E-supplemented rats. The magnitude of response of different tissues varied with increasing levels of dietary tocopherol. The results support previous findings on the effects of oral contraceptives on plasma cholesterol levels and lipoprotein distribution.
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