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  • Title: Searching for a postpartum contraceptive.
    Author: Perez-palacios G, Garza-flores J.
    Journal: Netw Res Triangle Park N C; 1988; 9(3):6. PubMed ID: 12315658.
    Abstract:
    A postpartum contraceptive that would extend the natural infertile period would provide a good method of birth spacing. Combined oral contraceptives reduce milk volume and change its composition. Progestin-only oral contraceptives (mini-pills), Norplant, injectable progestin contraceptives, and 1-norgestrel-medicated IUDs have all been found to result in significant amounts of progestin in breast milk. A progesterone-based postpartum contraceptive appears to be the best method, but clinical trials with subdermal progesterone pellets showed that they were poorly tolerated. The National Institute of Nutrition S. Zubiran, Mexico City, is currently conducting Phase I trials of a progesterone-based injectable contraceptive that provides a steady release of progesterone over a 2-3 month period.
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