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  • Title: Will American women want quinacrine?
    Journal: Contracept Technol Update; 1994 Apr; 15(4):48-50. PubMed ID: 12318751.
    Abstract:
    The quinacrine method of nonsurgical sterilization proves to be simple and inexpensive, but it has not yet proved to be safe and effective. If it can indeed be deemed safe and effective based on US standards, providers and women will compare it favorably with surgical sterilization. In December, 1993, a US radiologist reversed 2 quinacrine-induced sterilizations in India using an angioplasty-like procedure to ream blocked tubes. An unmet need for female surgical sterilization exists in the US, mainly because many women cannot pay for it and Title X funded programs have limited time and money to provide female sterilizations. If quinacrine can be proved to be safe and effective, and the Office of Population Affairs endorses the quinacrine method, Title X funded family planning programs would likely add it to their contraceptive options. US women who would likely accept the quinacrine method include those who have completed their families, do not want to use long-acting methods, and do not want any more children. Its side effects may make quinacrine unacceptable to some women, except perhaps those who greatly fear surgery. It is this fear and the pain, incapacitation, and even death that sometimes follow laparoscopic sterilization that may make quinacrine attractive to US women. USAID does not provide quinacrine pellets to family planning programs because the US Food and Drug Administration has not approved it. Proponents of quinacrine think that US women should be offered quinacrine as a choice now, especially women at risk for complications of surgical sterilization or who fear surgery. They should be fully informed of quinacrine's higher failure rate but lower complication rate. The quinacrine method of nonsurgical sterilization should be added as one more contraceptive option. It would not likely replace surgical sterilization.
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