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  • Title: Respiratory distress in newborn.
    Author: Kumar A, Bhat BV.
    Journal: Indian J Matern Child Health; 1996; 7(1):8-10. PubMed ID: 12320381.
    Abstract:
    The incidence of neonatal respiratory distress (RD) ranges from 2.2% to 7.6% in developed countries and from 0.7% to 8.3% in India. A study conducted in Pondicherry, India, found the incidence of neonatal RD to be 6.7%. The leading cause of neonatal RD is transient tachypnea (50-60% of RD cases) followed by infections (pneumonia, sepsis, or meningitis), meconium aspiration, and hyaline membrane disease (HMD). Significant predictors of neonatal RD include prematurity, malpresentation, abnormal delivery, premature rupture of membranes, fetal distress, multiple pregnancy, male sex, and low apgar score at birth. The case fatality rate for RD in India is 30-40%. In the Pondicherry study, it was 19%. Case fatality is highest for newborns with HMD (20-40% in developed countries and 50-75% in India). It ranges from 14.3% to 30.37% for meconium aspiration-related RD deaths. RD incidence and subsequent infant mortality can be reduced by improved prenatal care, early detection and referral of high risk pregnancies, closer links between referral hospitals and health centers, close monitoring of labor to detect fetal distress, and early intervention when indicated. In cases of RD, adequate and immediate resuscitation, oxygen supplementation, maintenance of optimal temperature, and time referral if RD lasts beyond two hours will reduce mortality. In cases of HMD and meconium aspiration, adequate ventilatory support and surfactant therapy will reduce mortality.
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