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  • Title: Serum cortisol level in lactating women using Progestasert system.
    Author: Askalani H, Badraoui MH, Mahrous T, Osman MI, Bayad MA, Ibrahim II, Abdalla MI.
    Journal: Popul Sci; 1981; (2):109-14. PubMed ID: 12339476.
    Abstract:
    This study is designed to reveal any possible change in serum cortisol levels of lactating mothers, both menstruating and amenorrheic, fitted with a progestasert intrauterine system immediately postpartum. The subjects of the study were 46 lactating females, in the 28-35 age group and of parity from 1 to 6. The women were classified into 2 groups: 1) menstruating and lactating females (n-26), with restored menstruation for at least 3 successive cycles prior to the study. These women were classified into a control group of 11 normally menstruating mothers not using any type of contraception, 9 mothers fitted with Cu T-200 IUDs, and 6 mothers fitted with a progestasert IUD. Both devices were inserted immediately postpartum. The 2nd group comprised amenorrheic and lactating mothers, delivered 2 months prior to the study, and classified as Progestasert users (n-8) and Cu T-200 users (n=12). Comparison of serum cortisol levels in the various categories revealed decreased levels in both IUD groups as compared to normal controls, at the onset of menstruation. However, a significant difference was only obtained between the non-IUD and Cu T-200 groups. Otherwise, no significant differences between the groups were ovbserved at day M-3. Serum cortisol levels were significantly raised in the control groups with the onset of menses which could be explained on the basis of menstrual stress. Serum cortisol levels were also determined in 2 groups of lactating amenorrheic mothers, 2 months after delivery, fitted with Progestasert and Cu T-200 IUDs. Results indicate non significant difference between the 2 groups. Based on these findings, it is concluded that the progestasert intrauterine system has no effect on cortisol levels of postpartum lactating women.
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