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  • Title: Mammogram synthesis using a 3D simulation. I. Breast tissue model and image acquisition simulation.
    Author: Bakic PR, Albert M, Brzakovic D, Maidment AD.
    Journal: Med Phys; 2002 Sep; 29(9):2131-9. PubMed ID: 12349935.
    Abstract:
    A method is proposed for generating synthetic mammograms based upon simulations of breast tissue and the mammographic imaging process. A computer breast model has been designed with a realistic distribution of large and medium scale tissue structures. Parameters controlling the size and placement of simulated structures (adipose compartments and ducts) provide a method for consistently modeling images of the same simulated breast with modified position or acquisition parameters. The mammographic imaging process is simulated using a compression model and a model of the x-ray image acquisition process. The compression model estimates breast deformation using tissue elasticity parameters found in the literature and clinical force values. The synthetic mammograms were generated by a mammogram acquisition model using a monoenergetic parallel beam approximation applied to the synthetically compressed breast phantom.
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