These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Restricted expression of mouse GCMa/Gcm1 in kidney and thymus.
    Author: Hashemolhosseini S, Hadjihannas M, Stolt CC, Haas CS, Amann K, Wegner M.
    Journal: Mech Dev; 2002 Oct; 118(1-2):175-8. PubMed ID: 12351183.
    Abstract:
    Mouse Glial Cells Missing a (mGCMa) belongs to a small family of transcription factors named after the prototypical GCM from Drosophila. mGCMa was expected to regulate gliogenesis, but instead found to be primarily expressed during development in trophoblasts of chorion and labyrinth. Its deletion causes abnormal placental labyrinth formation and results in embryonic lethality. Here we identify kidney and thymus as sites of mGCMa expression. In thymus, mGCMa is restricted to few small clusters of cells, in kidney to the S3 segment of proximal tubules. mGCMa expression is primarily postnatal, arguing for a role in organ function rather than organ development.
    [Abstract] [Full Text] [Related] [New Search]