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  • Title: GABAergic circuitry in the dorsal division of the cat medial geniculate nucleus.
    Author: Coomes DL, Bickford ME, Schofield BR.
    Journal: J Comp Neurol; 2002 Nov 04; 453(1):45-56. PubMed ID: 12357431.
    Abstract:
    Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the thalamus. We used postembedding immunocytochemistry to examine the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the cat medial geniculate nucleus (MGN). Three groups of GABA-positive profiles participate in synapses: axon terminals, dendrites, and presynaptic dendrites. The presynaptic GABA-positive terminals target mainly GABA-negative dendrites. The GABA-positive postsynaptic profiles receive input primarily from GABA-negative axons. The results indicate that the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the MGN nucleus is very similar to that in other thalamic nuclei.
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