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  • Title: [Changes in the serum activity of lysosome enzymes in rats after application of the insecticide propoxur (Baygon)].
    Author: Apostolov I, Ribarova F, Pramatarova V.
    Journal: Probl Khig; 1975; 1():207-10. PubMed ID: 1236002.
    Abstract:
    The effect of repeated peroral introduction (4 times) of 1/4 and 1/20 LD50 of monomethylcarbamate insecticide Propoxur (Baygon) on the activity of two lysosomal enzymes (beta-N-acetylglucosaminidase and alpha-mannosidase) is studied in the serum of white male rats with starting weight 300 g. Upon using the higher dose, a statistically significant rise (p less than 0.02) of the activity of either of the enzymes is established. The results obtained are interpreted as a sign of impaired permeability of the lysosomal and cell membrane.
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