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  • Title: [Efficiency and safety of a long-lasting form of diltiazem in the treatment of hypertensive patients with ischemic heart disease].
    Author: Svetyĭ LI, Pavlova LI, Mazerkina IA.
    Journal: Klin Med (Mosk); 2002; 80(8):58-61. PubMed ID: 12360623.
    Abstract:
    Antianginal and hypotensive efficacy of etizem was studied in 40 patients with ischemic heart disease (IHD), stable angina of effort (moderate-to-severe) for 4 weeks and 43 patients with arterial hypertension (mild-to-moderate) for 12 weeks. A course treatment with etizem lowered mean 24 hour, mean diurnal and mean nocturnal blood pressure (both systolic and diastolic, normalized blood pressure in most cases of abnormal 24 hour diastolic blood pressure profile. Etizem also significantly improved left ventricular diastolic function but failed to do so in relation to myocardial mass of the left ventricle.
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