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  • Title: Pyrrole analogues of chloramphenicol. III. Synthesis and antibacterial activity of DL-threo-1-(1-methylsulfonylpyrrole-3-yl)-2-dichloroacetamidopropane-1,3-diol.
    Author: Krajewska D, Dabrowska M, Jakoniuk P, Rózański A.
    Journal: Acta Pol Pharm; 2002; 59(2):127-32. PubMed ID: 12365604.
    Abstract:
    A seven-stage synthesis of a pyrrole analogue of chloramphenicol (9) is described. The compound exhibits a significant antibacterial activity, over the 3% to 50% range of the chloramphenicol activity: over the 6% to 100% range of the thiamphenicol activity and florfenicol.
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