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Title: Cell density dependence of the aggregation characteristics of the cellular slime mould Dictyostelium discoideum. Author: Hashimoto Y, Cohen MH, Robertson A. Journal: J Cell Sci; 1975 Oct; 19(1):215-29. PubMed ID: 1236856. Abstract: We have measured fruiting body density and spore formation efficiency in Dictyostelium discoideum as functions of initial cell density. Experiments were performed on agar made up with distilled water and on buffered agar. Minor differences are seen; these are discussed. The functions show 4 regions of density dependence which can be accounted for by changes in aggregation characteristics with density and changes in the efficiency of spore differentiation. The results are discussed in terms of the relaying mechanism for signal propagation controlling cell aggregation. They extend earlier measurements by Bonner & Dodd and by Hohl & Raper, supply data for a quantitative model of the aggregation process, allow estimates of signal range, and show the importance of entrainment between neighbouring centres in defining aggregation territories.[Abstract] [Full Text] [Related] [New Search]