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  • Title: [In vitro differentiation of cartilage from cephalic neural crest of Pleurodeles waltlii Michah (author's transl)].
    Author: Corsin J.
    Journal: J Embryol Exp Morphol; 1975 Apr; 33(2):335-42. PubMed ID: 1236925.
    Abstract:
    Parts of cephalic neural crest of Pleurodeles waltlii have been cultivated in vitro alone or in explants containing other cellular components. It was hoped that these experiments would establish under what conditions cephalic neural crest cells can differentiate into chondroblasts. It has been demonstrated that this differentiation is possible only under the influence of the dorsal mesoderm and foregut endoderm. It appears that neural crest cells are relatively pluripotent and progressively differentiate in response to local environmental factors.
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