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  • Title: [Optimization of the nutrient medium for the biosynthesis of phytotoxic metabolites of Myrothecium verrucaria VKMF-183].
    Author: Elisashvili TA, Borovkov AV.
    Journal: Prikl Biokhim Mikrobiol; 1975; 11(6):877-9. PubMed ID: 1239763.
    Abstract:
    By means of mathematical planning of the experiment optimal concentrations of components of the nutrient medium were found for the biosynthesis of phytotoxic metabolites by the soil fungus Myrothecium verrucaria VKMF-183. The composition of the optimized medium were: glucose--8%, KH2PO4--0.05%, asparagine--0.35%, ammonium tartrate--0.07%, MgSO4--0.03%, solution of trace elements--0.1%. The accumulation of phytotoxic metabolites in the above medium was 2.4 times higher than in the initial medium.
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