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  • Title: Hepatocellular carcinoma originating from intramural cells in the bile duct.
    Author: Hasegawa K, Kubota K, Mori M, Midorikawa Y, Takayama T, Makuuchi M.
    Journal: Hepatogastroenterology; 2002; 49(48):1688-91. PubMed ID: 12397767.
    Abstract:
    We report a case of intramural hepatocellular carcinoma in the right anterior bile duct associated with another carcinoma in segment IV of the liver. The cancers might have been of multicentric origin because they were separated by about 5 cm of non-cancerous liver parenchyma and their pathological findings were different from each other. The intramural carcinoma pushed up the biliary mucosa and extended into the bile duct lumen. It is difficult to make a reasonable assumption about origin of the tumor, but we consider that the carcinoma might have originated in intramural cells in the bile duct which were different from hepatocytes in the liver parenchyma.
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