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Title: Evans blue: a specific inhibitor of factor VIII-induced platelet agglutination. Author: Kirby EP. Journal: Thromb Diath Haemorrh; 1975 Dec 15; 34(3):770-9. PubMed ID: 1239827. Abstract: Low concentrations of Evans Blue (less than 1 muM) inhibit the agglutination of formalin-treated platelets by bovine Factor VIII or by human Factor VIII in the presence of the antibiotic ristocetin. Evans Blue is a specific inhibitor of this reaction and acts by inhibiting the binding of Factor VIII to the platelet surface.[Abstract] [Full Text] [Related] [New Search]